Before going to the detailed differences, the simple most and trade mark difference is that osteoporosis is always QUANTITATIVE disorder while osteomalacia is always QUALITATIVE.

Osteoporosis is quantitatively inadequate bone mass, while osteomalacia is qualitatively inadequate mineralization.


It is a disorder of loss in bone mass, generally seen in elder people especially in women after menopause. It is characterized by brittle, porous, and weak bones. Therefore these people are more likely to fracture their bones even after a simple fall from standing position. The condition exacerbates with vitamin D and calcium deficiency in the diet. These people are very prone to different pathological conditions. Their bones density decreased although they have normal minerals i.e normal calcium, phosphorous etc. symptoms appears when fractures occur in the porous bones.


Intake of calcium rich foods, exposure to sunlight.


A condition of excessive and prolonged deficiencies in vitamin D and minerals i.e inadequate calcium and phosphorous, which weaken and soften the bones. Besides dietary deficiency of vitamins and minerals, kidney and digestive disorders may also cause osteomalacia. Vitamin D absorbs calcium and makes the bones hard and strong. vitamin D deficiency will lead to soft bones, muscles spasm, cramping and tangling in the limbs.


  1. People with little exposure to sunlight
  2. Pregnant and breast feeding women
  3. People with liver and kidney diseases, stomach ulcers etc
  4. Hyperparathyroidic people
  5. people with nutrition problems


Osteomalacia is treated with vitamin D (calciferol). The dose changes according to age and body conditions of the patient.


  1. Calcium level is normal in osteoporosis, while low in osteomalacia
  2. Phosphate level is normal in osteoporosis, while low or normal in osteomalacia
  3. Parathyroid level is normal in osteoporosis, while high in osteomalacia
  4. Alkaline phosphatase (ALP) is normal in osteoporosis, while high in osteomalacia.
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He is owner of this website. He is MBBS student in Bannu Medical College, Khyber Medical University Pakistan.

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